Class
Penicillin
Dose
250-500 mg tds or 1g bd with or without food
Child: 15–25 mg/kg (MAX 500mg) q8h. For severe infections up to 30 mg/kg (maximum 1 g) every 8 hours can be used.
Indication
Chronic bronchitis, Acute bacterial otitis media, Sinusitis, CAP (community-acquired pneumonia),
Gonococcal infection, Epididymo-orchitis, acute prostatitis, acute pyelonephritis, UTI
Endocarditis prophylaxis in high-risk patients
Acute cholecystitis, peritonitis, eradication of H. pylori
Adverse Effects
Amoxycillin/ampicillin rash, diarrhoea, nausea. superinfection
Label
Liquid: 6, 7a, D
Counselling
If the symptoms of your infection do not improve within a few days, or if they become worse, tell your doctor.
Monitoring Points
Monitor complete blood count and renal and hepatic function during prolonged high-dose treatment (>10 days).
A little bit of a diarrhoea is normal. If severe go and see a doctor.
Helpful Notes
Your Notes
Class: penicillin antibacterial
Indications
Exacerbation of chronic bronchitis and CAP; acute otitis media, sinusitis; gonococcal infection; UTIs and H. pylori eradication (with other agents)
Dosage (range/frequency/timing)
Adult: 250–500 mg q8h, or 1 g bd. Dose of 1 g q8h may be used in severe infections (eg pneumonia)
Child: 7.5–25 mg/kg (max 500 mg) q8h. Max 30 mg/kg (or 1 g) q8h.
Adverse effects
Pustular drug eruption; widespread non-immune-mediated maculopapular rash – often occurs after >7 days treatment and resolves 1–7 days after treatment is stopped, or after 6–14 days if it continues.
Patient counselling points
Tablet/capsule can be taken with or without food.
Oral suspensions
(14 days)
